That said, provided you do have the right permissions, you could as well disable Skype in a quite simple manner, so that even if installed, it won’t start automatically when logging on to Windows 7/10 or alternatively it would run only in the background and won’t interfere with your daily work. Therefore, the only feasible way to uninstall it would be to uninstall Office 365 altogether. Skype for Business is integrated into Office 365, and doesn’t appear as an independent entry in the Programs and Features list. Disable and Remove Skype for Business 365 / 2019